SRR7986800 - Western honey bee

Basic Information

Run: SRR7986800

Assay Type: WGS

Bioproject: PRJNA494922

Biosample: SAMN10185828

Bytes: 3073982295

Center Name: UNIVERSITY OF EDINBURGH

Sequencing Information

Instrument: Illumina HiSeq 2500

Library Layout: PAIRED

Library Selection: unspecified

Platform: ILLUMINA

Geographic Information

Country: United Kingdom

Continent: Europe

Location Name: United Kingdom

Latitude/Longitude: 56.3 N 3.46 W

Sample Information

Host: Western honey bee

Isolation: -

Biosample Model: Metagenome or environmental

Collection Date: 2015-07

Taxonomic Classification

Potential Symbionts

About Potential Symbionts

This table shows potential symbiont identified in the metagenome sample. Matches are scored based on:

Relative abundance in the sample
Species-level matches with known symbionts
Host insect order matches with reference records
Completeness and richness of functional records

Note: only the three highest scoring comparison records were retained for each symbiont species or genus in the sample

Based on our current records database, this section aims to identify potential functional symbionts in this metagenome sample, with scoring based on:

Relative abundance in sample
Species-level matches with known symbionts
Host insect order matches
Functional record completeness

Note: Showing top 3 highest scoring records for each species/genus

Symbiont Name	Record	Host Species	Function	Abundance	Score Score Composition: Symbiont Abundance Species match bonus Host match bonus Function richness Higher scores indicate stronger symbiotic relationship potential
Gilliamella apicola Species-level Match Host Order Match	RISB0102	Apis mellifera Order: Hymenoptera	Gilliamella apicola carries the gene for the desaturase FADS2, which is able to metabolize polyunsaturated fatty acids from pollen and synthesize endocannabinoid, a lipogenic neuroactive substance, thereby modulating reward learning and memory in honeybees.	4.03%	24.0
Bifidobacterium asteroides Species-level Match Host Order Match	RISB0174	Apis mellifera Order: Hymenoptera	Bifidobacterium provides complementary demethylation service to promote Gilliamella growth on methylated homogalacturonan, an enriched polysaccharide of pectin. In exchange, Gilliamella shares digestive products with Bifidobacterium, through which a positive interaction is established	0.08%	20.1
Streptomyces sp. T12 Species-level Match Host Order Match	RISB0943	Polybia plebeja Order: Hymenoptera	this bacterium produces antimicrobial compounds that are active against Hirsutella citriformis, a natural fungal enemy of its host, and the human pathogens Staphylococcus aureus and Candida albicans	0.70%	19.7
Streptomyces sp. T12 Species-level Match Host Order Match	RISB2334	Sirex noctilio Order: Hymenoptera	degrading woody substrates and that such degradation may assist in nutrient acquisition by S. noctilio, thus contributing to its ability to be established in forested habitats worldwide	0.70%	19.4
Gilliamella apicola Species-level Match Host Order Match	RISB1945	Apis cerana Order: Hymenoptera	None	4.03%	19.0
Candidatus Hamiltonella defensa Species-level Match Host Order Match	RISB2027	Lysiphlebus fabarum Order: Hymenoptera	symbiont provided strong protection against L. fabarum and Aphidius colemani, but there was no evidence that H. defensa-infected aphids were more resistant to the other parasitoid species	0.02%	18.8
Snodgrassella alvi Species-level Match Host Order Match	RISB1423	Bombus spp. Order: Hymenoptera	The bumble bee microbiome slightly increases survivorship when the host is exposed to selenate	1.85%	18.7
Pseudomonas sp. CIP-10 Species-level Match Host Order Match	RISB1564	Liometopum apiculatum Order: Hymenoptera	None	3.37%	18.4
Spiroplasma sp. SV19 Species-level Match Host Order Match	RISB1353	Cephus cinctus Order: Hymenoptera	The bacterium also encoded biosynthetic pathways for essential vitamins B2, B3, and B9. We identified putative Spiroplasma virulence genes: cardiolipin and chitinase.	0.01%	18.3
Streptomyces sp. T12 Species-level Match Host Order Match	RISB1134	mud dauber wasp Order: Hymenoptera	secondary metabolites derived from a Streptomyces sp. displayed significant inhibitory activity against hexokinase II	0.70%	18.0
Bacillus sp. S3 Species-level Match Host Order Match	RISB0218	Xylocopa appendiculata Order: Hymenoptera	strains biodegraded polyethylene terephthalate PET powder, broke it into its degradation products	0.04%	17.0
Bacillus sp. DX3.1 Species-level Match Host Order Match	RISB0218	Xylocopa appendiculata Order: Hymenoptera	strains biodegraded polyethylene terephthalate PET powder, broke it into its degradation products	0.03%	17.0
Bacillus sp. DTU_2020_1000418_1_SI_GHA_SEK_038 Species-level Match Host Order Match	RISB0218	Xylocopa appendiculata Order: Hymenoptera	strains biodegraded polyethylene terephthalate PET powder, broke it into its degradation products	0.02%	17.0
Snodgrassella alvi Species-level Match Host Order Match	RISB1947	Apis cerana Order: Hymenoptera	None	1.85%	16.9
Wolbachia Host Order Match	RISB0190	Encarsia formosa Order: Hymenoptera	Wolbachia's parthenogenesis-induction feminization factor (piff) gene modulates sex determination in Encarsia formosa by regulating doublesex (dsx) expression. When Wolbachia is removed, female-specific dsx decreases while male-specific dsx increases, resulting in haploid male offspring	1.70%	16.7
Lactobacillus apis Species-level Match Host Order Match	RISB1556	Apis florea Order: Hymenoptera	None	1.69%	16.7
Wolbachia Host Order Match	RISB1584	Nasonia vitripennis Order: Hymenoptera	there were few significant changes in immune or reproductive proteins between samples with and without Wolbachia infection. Differentially expressed proteins were involved in the binding process, catalytic activity, and the metabolic process	1.70%	16.5
Arsenophonus sp. aPb Species-level Match Host Order Match	RISB0982	Vespula penalica Order: Hymenoptera	Arsenophonus sp. has been negatively associated with honeybee hive health	0.01%	16.5
Candidatus Hamiltonella defensa Species-level Match Host Order Match	RISB1958	Aphelinus abdominalis Order: Hymenoptera	Provides resistance to certain parasitic wasps, such as Aphidius	0.02%	16.3
Candidatus Hamiltonella defensa Species-level Match Host Order Match	RISB1597	Aphelinus glycinis Order: Hymenoptera	increased progeny and female progeny size of Aphelinus glycinis	0.02%	16.3
Stenotrophomonas maltophilia Species-level Match Host Order Match	RISB2004	Trichogramma chilonis Order: Hymenoptera	could significantly increase both female count	0.28%	16.2
Arsenophonus nasoniae Species-level Match Host Order Match	RISB0428	Nasonia vitripennis Order: Hymenoptera	male killing	0.02%	15.3
Wolbachia Host Order Match	RISB2601	Asobara tabida Order: Hymenoptera	Wolbachia is necessary for oogenesis in these A. tabida strains，aposymbiotic female wasps were completely incapable of producing mature oocytes and therefore could not reproduce	1.70%	15.2
Providencia rettgeri Species-level Match Host Order Match	RISB1352	Nasonia vitripennis Order: Hymenoptera	None	0.16%	15.2
Arsenophonus nasoniae Species-level Match Host Order Match	RISB0366	Pachycrepoideus vindemmiae Order: Hymenoptera	None	0.02%	15.0
Pseudomonas sp. REST10 Species-level Match Host Order Match	RISB1564	Liometopum apiculatum Order: Hymenoptera	None	0.01%	15.0
Apibacter Host Order Match	RISB0603	Apis cerana Order: Hymenoptera	The acquisition of genes for the degradation of the toxic monosaccharides potentiates Apibacter with the ability to utilize the pollen hydrolysis products, at the same time enabling monosaccharide detoxification for the host	0.05%	14.5
Candidatus Blochmanniella Host Order Match	RISB2542	Camponotus Order: Hymenoptera	Blochmannia provide essential amino acids to its host,Camponotus floridanus, and that it may also play a role in nitrogen recycling via its functional urease	0.13%	13.3
Bartonella Host Order Match	RISB1673	Apis mellifera Order: Hymenoptera	a gut symbiont of insects and that the adaptation to blood-feeding insects facilitated colonization of the mammalian bloodstream	0.71%	13.3
Candidatus Blochmanniella Host Order Match	RISB1827	Camponotus floridanus Order: Hymenoptera	a modulation of immune gene expression which may facilitate tolerance towards the endosymbionts and thus may contribute to their transovarial transmission	0.13%	13.2
Pseudomonas sp. CIP-10 Species-level Match	RISB1622	Dendroctonus valens Order: Coleoptera	volatiles from predominant bacteria regulate the consumption sequence of carbon sources d-pinitol and d-glucose in the fungal symbiont Leptographium procerum, and appear to alleviate the antagonistic effect from the fungus against RTB larvae	3.37%	13.2
Bacteroides Host Order Match	RISB0256	Leptocybe invasa Order: Hymenoptera	Differences in Male-Killing Rickettsia Bacteria between Lineages of the Invasive Gall-Causing Pest Leptocybe invasa	0.60%	12.9
Candidatus Blochmanniella Host Order Match	RISB2448	Camponotus floridanus Order: Hymenoptera	nutritional contribution of the bacteria to host metabolism by production of essential amino acids and urease-mediated nitrogen recycling	0.13%	12.9
Bacteroides Host Order Match	RISB2590	Encarsia pergandiella Order: Hymenoptera	associated with thelytokous parthenogenetic reproduction in Encarsia, a genus of parasitoid wasps	0.60%	12.5
Apilactobacillus Host Order Match	RISB0475	Apis mellifera Order: Hymenoptera	A. kunkeei alleviated acetamiprid-induced symbiotic microbiota dysregulation and mortality in honeybees	0.03%	12.1
Burkholderia Host Order Match	RISB2149	Osmia bicornis Order: Hymenoptera	may be essential to support Osmia larvae in their nutrient uptake	0.02%	11.3
Buchnera aphidicola Species-level Match	RISB0236	Acyrthosiphon pisum Order: Hemiptera	Buchnera the nutritional endosymbiont of A. pisum is located inside of bacteriocytes and requires aspartate from the aphid host, because it cannot make it de novo. Further Buchnera needs aspartate for the biosynthesis of the essential amino acids lysine and threonine, which the aphid and Buchnera require for survival	1.06%	11.1
Buchnera aphidicola Species-level Match	RISB2485	Macrosiphum euphorbiae Order: Hemiptera	symbiont expression patterns differ between aphid clones with differing levels of virulence, and are influenced by the aphids' host plant. Potentially, symbionts may contribute to differential adaptation of aphids to host plant resistance	1.06%	10.8
Escherichia coli Species-level Match	RISB1339	Manduca sexta Order: Lepidoptera	modulate immunity-related gene expression in the infected F0 larvae, and also in their offspring, triggered immune responses in the infected host associated with shifts in both DNA methylation and histone acetylation	1.11%	10.4
Klebsiella pneumoniae Species-level Match	RISB2185	Scirpophaga incertulas Order: Lepidoptera	The ability of these arthropods to feed on wood, foliage and detritus is likely to involve catalysis by different types of cellulases/hemicellulases that are secreted by gut microbiota to digest the structural and recalcitrant lignocellulosic residues in their foods.	0.41%	10.4
Burkholderia Host Order Match	RISB2101	Formica exsecta Order: Hymenoptera	produce antibiotics	0.02%	10.4
Lonsdalea Host Order Match	RISB1321	Vespa mandarinia Order: Hymenoptera	None	0.38%	10.4
Burkholderia Host Order Match	RISB2580	Tetraponera binghami Order: Hymenoptera	Nitrogen fixation	0.02%	10.4
Lactococcus lactis Species-level Match	RISB0131	Ceratitis capitata Order: Diptera	The intestinal microbiota structure was significantly influenced by the probiotic treatment while still maintaining a stable core dominant community of Enterobacteriacea. The colony with these microbiome had the most improved potential functions in terms of gut microbes as well as the carbohydrates active enzymes most improved potential functions.	0.23%	10.2
Yersinia Host Order Match	RISB0407	Anaphes nitens Order: Hymenoptera	None	0.11%	10.1
Pantoea agglomerans Species-level Match	RISB2197	Termitidae Order: Blattodea	The ability of these arthropods to feed on wood, foliage and detritus is likely to involve catalysis by different types of cellulases/hemicellulases that are secreted by gut microbiota to digest the structural and recalcitrant lignocellulosic residues in their foods.	0.09%	10.1
Paenibacillus polymyxa Species-level Match	RISB2195	Termitidae Order: Blattodea	The ability of these arthropods to feed on wood, foliage and detritus is likely to involve catalysis by different types of cellulases/hemicellulases that are secreted by gut microbiota to digest the structural and recalcitrant lignocellulosic residues in their foods.	0.09%	10.1
Apibacter Host Order Match	RISB0604	Apis cerana Order: Hymenoptera	None	0.05%	10.1
Listeria monocytogenes Species-level Match	RISB2308	Drosophila melanogaster Order: Diptera	L. monocytogenes infection disrupts host energy metabolism by depleting energy stores (triglycerides and glycogen) and reducing metabolic pathway activity (beta-oxidation and glycolysis). The infection affects antioxidant defense by reducing uric acid levels and alters amino acid metabolism. These metabolic changes are accompanied by melanization, potentially linked to decreased tyrosine levels.	0.04%	10.0
Serratia marcescens Species-level Match	RISB0120	Nezara viridula Order: Hemiptera	plays an important role in interactions between insects and plants and could therefore be considered a valuable target for the development of sustainable pest control strategies;transmitted bacteria impacted plant chemical defenses and were able to degrade toxic plant metabolites, aiding the shield bug in its nutrition	0.03%	10.0
Francisella tularensis Species-level Match	RISB1907	Bombyx mori Order: Lepidoptera	After infection with F. tularensis, the induction of melanization and nodulation, which are immune responses to bacterial infection, were inhibited in silkworms. Pre-inoculation of silkworms with F. tularensis enhanced the expression of antimicrobial peptides and resistance to infection by pathogenic bacteria.	0.03%	10.0
Staphylococcus gallinarum Species-level Match	RISB0945	Callosobruchus maculatus Order: Coleoptera	The strain encodes complete biosynthetic pathways for the production of B vitamins and amino acids, including tyrosine; A carbohydrate-active enzyme search revealed that the genome codes for a number of digestive enzymes, reflecting the nutritional ecology of C. maculatus	0.02%	10.0
Candidatus Pantoea carbekii Species-level Match	RISB1046	Halyomorpha halys Order: Hemiptera	provides its host with essential nutrients, vitamins, cofactors and protection of the most vulnerable stages of early development (1st nymphal stages). Pantoea carbekii is highly stress tolerant, especially once secreted to cover the eggs, by its unique biofilm-formation properties, securing host offspring survival	0.01%	10.0
Enterococcus mundtii Species-level Match	RISB1733	Spodoptera littoralis Order: Lepidoptera	actively secretes a stable class IIa bacteriocin (mundticin KS) against invading bacteria, including the opportunistic pathogens E. faecalis and E. casseliflavus, but not against other gut residents, facilitating the normal development of host gut microbiota	0.01%	10.0
Buchnera aphidicola Species-level Match	RISB0685	Acyrthosiphon pisum Order: Hemiptera	It supplies the host with vitamins and essential amino acids, such as arginine and methionine that aphids cannot synthesize or derive insufficiently from their diet, the phloem sap of plants	1.06%	9.9
Serratia marcescens Species-level Match	RISB0477	Spodoptera litura Order: Lepidoptera	The ingestion of bacteria negatively affected the development and nutritional physiology of insect. The bacteria after successful establishment started degrading the gut wall and invaded the haemocoel thereby causing the death of the host.	0.03%	9.8
Enterococcus mundtii Species-level Match	RISB0476	Spodoptera litura Order: Lepidoptera	The ingestion of bacteria negatively affected the development and nutritional physiology of insect. The bacteria after successful establishment started degrading the gut wall and invaded the haemocoel thereby causing the death of the host.	0.01%	9.8
Acinetobacter sp. Marseille-Q1620 Species-level Match	RISB0730	Curculio chinensis Order: Coleoptera	Acinetobacter sp. in C. chinensis enriched after treating with saponin, and when incubating bacteria with saponin for 72 h, saponin content significantly decreased from 4.054 to 1.867 mg/mL (by 16S rRNA metagenome sequencing and HPLC)	0.04%	9.7
Serratia marcescens Species-level Match	RISB0747	Rhodnius prolixus Order: Hemiptera	Acinetobacter sp. in C. chinensis enriched after treating with saponin, and when incubating bacteria with saponin for 72 h, saponin content significantly decreased from 4.054 to 1.867 mg/mL (by 16S rRNA metagenome sequencing and HPLC)	0.03%	9.7
Candidatus Nasuia deltocephalinicola Species-level Match	RISB2283	Nephotettix cincticeps Order: Hemiptera	Oral administration of tetracycline to nymphal N. cincticeps resulted in retarded growth, high mortality rates, and failure in adult emergence, suggesting important biological roles of the symbionts for the host insect	0.02%	9.4
Clostridium sp. DL-VIII Species-level Match	RISB2301	Pyrrhocoris apterus Order: Hemiptera	could play an important role for the insect by degrading complex dietary components, providing nutrient supplementation, or detoxifying noxious chemicals (e.g. cyclopropenoic fatty acids or gossypol) in the diet	0.10%	9.3
Clostridium sp. LQ25 Species-level Match	RISB2301	Pyrrhocoris apterus Order: Hemiptera	could play an important role for the insect by degrading complex dietary components, providing nutrient supplementation, or detoxifying noxious chemicals (e.g. cyclopropenoic fatty acids or gossypol) in the diet	0.07%	9.3
Stenotrophomonas maltophilia Species-level Match	RISB1122	Bombyx mori Order: Lepidoptera	facilitate host resistance against organophosphate insecticides, provides essential amino acids that increase host fitness and allow the larvae to better tolerate the toxic effects of the insecticide.	0.28%	9.3
Clostridium sp. MB40-C1 Species-level Match	RISB2301	Pyrrhocoris apterus Order: Hemiptera	could play an important role for the insect by degrading complex dietary components, providing nutrient supplementation, or detoxifying noxious chemicals (e.g. cyclopropenoic fatty acids or gossypol) in the diet	0.06%	9.3
Pantoea ananatis Species-level Match	RISB1671	Spodoptera frugiperda Order: Lepidoptera	modulate plant defense, downregulated the activity of the plant defensive proteins polyphenol oxidase and trypsin proteinase inhibitors (trypsin PI) but upregulated peroxidase (POX) activity in tomatoresponses	0.08%	9.3
Lactobacillus sp. IBH004 Species-level Match	RISB0292	Lymantria dispar asiatica Order: Lepidoptera	Beauveria bassiana infection-based assays showed that the mortality of non-axenic L. dispar asiatica larvae was significantly higher than that of axenic larvae at 72 h.	0.89%	9.3
Mammaliicoccus sciuri Species-level Match	RISB0075	Bombyx mori Order: Lepidoptera	could produce a secreted chitinolytic lysozyme (termed Msp1) to damage fungal cell walls，completely inhibit the spore germination of fungal entomopathogens Metarhizium robertsii and Beauveria bassiana	0.18%	9.2
Candidatus Portiera aleyrodidarum Species-level Match	RISB1193	Bemisia tabaci Order: Hemiptera	synthesizing essential amino acid (e.g. tryptophan, leucine and L-Isoleucine), Bemisia tabaci provides vital nutritional support for growth, development and reproduction	0.69%	9.1
Staphylococcus xylosus Species-level Match	RISB2497	Anticarsia gemmatalis Order: Lepidoptera	allow the adaptation of this insect to plants rich in protease inhibitors, minimizing the potentially harmful consequences of protease inhibitors from some of this insect host plants, such as soybean	0.05%	9.0
Candidatus Schneideria nysicola Species-level Match	RISB0872	Nysius sp. Order: Hemiptera	synthesize four B vitamins(Pan, pantothenate;Fol, folate; Rib, riboflavin; Pyr, pyridoxine) and five Essential Amino Acids(Ile, isoleucine; Val, valine; Lys, lysine; Thr, threonine; Phe, phenylalanine)	0.01%	9.0
Candidatus Carsonella ruddii Species-level Match	RISB0394	Cacopsylla pyricola Order: Hemiptera	Carsonella produces most essential amino acids (EAAs) for C. pyricola, Psyllophila complements the genes missing in Carsonella for the tryptophan pathway and synthesizes some vitamins and carotenoids	0.02%	9.0
Enterococcus mundtii Species-level Match	RISB2494	Anticarsia gemmatalis Order: Lepidoptera	allow the adaptation of this insect to plants rich in protease inhibitors, minimizing the potentially harmful consequences of protease inhibitors from some of this insect host plants, such as soybean	0.01%	9.0
Klebsiella michiganensis Species-level Match	RISB1052	Bactrocera dorsalis Order: Diptera	K. michiganensis BD177 has the strain-specific ability to provide three essential amino acids (phenylalanine, tryptophan and methionine) and two vitamins B (folate and riboflavin) to B. dorsalis	0.02%	8.9
Acinetobacter pittii Species-level Match	RISB1977	Blattella germanica Order: Blattodea	gut microbiota contributes to production of VCAs that act as fecal aggregation agents and that cockroaches discriminate among the complex odors that emanate from a diverse microbial community	0.07%	8.9
Acinetobacter sp. Marseille-Q1620 Species-level Match	RISB1978	Blattella germanica Order: Blattodea	gut microbiota contributes to production of VCAs that act as fecal aggregation agents and that cockroaches discriminate among the complex odors that emanate from a diverse microbial community	0.04%	8.9
Escherichia coli Species-level Match	RISB0128	Tribolium castaneum Order: Coleoptera	may produce 4,8-dimethyldecanal (DMD) production that is strongly associated with attraction to females and host pheromone communication	1.11%	8.8
Lactococcus lactis Species-level Match	RISB0967	Oulema melanopus Order: Coleoptera	contribute to the decomposition of complex carbohydrates, fatty acids, or polysaccharides in the insect gut. It might also contribute to the improvement of nutrient availability.	0.23%	8.8
Lactobacillus sp. wkB8 Species-level Match	RISB0292	Lymantria dispar asiatica Order: Lepidoptera	Beauveria bassiana infection-based assays showed that the mortality of non-axenic L. dispar asiatica larvae was significantly higher than that of axenic larvae at 72 h.	0.29%	8.7
Bifidobacterium asteroides Species-level Match	RISB0616	Spodoptera frugiperda Order: Lepidoptera	Strain wkB204 grew in the presence of amygdalin as the sole carbon source, suggesting that this strain degrades amygdalin and is not susceptible to the potential byproducts	0.08%	8.5
Sphingobacterium sp. ML3W Species-level Match	RISB2227	Leptinotarsa decemlineata Order: Coleoptera	Colorado potato beetle (Leptinotarsa decemlineata) larvae exploit bacteria in their oral secretions to suppress antiherbivore defenses in tomato (Solanum lycopersicum)	0.02%	8.4
Sphingobacterium sp. WM Species-level Match	RISB2227	Leptinotarsa decemlineata Order: Coleoptera	Colorado potato beetle (Leptinotarsa decemlineata) larvae exploit bacteria in their oral secretions to suppress antiherbivore defenses in tomato (Solanum lycopersicum)	0.01%	8.4
Candidatus Gullanella endobia Species-level Match	RISB1885	Ferrisia virgata Order: Hemiptera	a nested symbiotic arrangement, where one bacterium lives inside another bacterium,occurred in building the mosaic metabolic pathways seen in mitochondria and plastids	0.01%	8.4
Morganella morganii Species-level Match	RISB0772	Delia antiqua Order: Diptera	showed significant volatile inhibition activity against fungal entomopathogen Fusarium moniliforme, Botryosphaeria dothidea and both Fusarium oxysporum respectively	0.07%	8.4
Blattabacterium cuenoti Species-level Match	RISB0133	Panesthiinae Order: Blattodea	enables hosts to subsist on a nutrient-poor diet; endosymbiont genome erosions are associated with repeated host transitions to an underground life	0.40%	8.3
Paenibacillus sp. 481 Species-level Match	RISB0774	Delia antiqua Order: Diptera	showed significant contact inhibition activity against fungal entomopathogen Fusarium moniliforme, Botryosphaeria dothidea and both Fusarium oxysporum respectively	0.05%	8.3
Lactococcus lactis Species-level Match	RISB0113	Bactrocera dorsalis Order: Diptera	increase the resistance of B. dorsalis to β-cypermethrin by regulating cytochrome P450 (P450) enzymes and α-glutathione S-transferase (GST) activities	0.23%	8.2
Wigglesworthia glossinidia Species-level Match	RISB0369	Glossina morsitans Order: Diptera	symbiont-derived factors, likely B vitamins, are critical for the proper function of both lipid biosynthesis and lipolysis to maintain tsetse fly fecundity	0.05%	8.2
Morganella morganii Species-level Match	RISB0008	Phormia regina Order: Diptera	deterred oviposition by female stable flies; The flies' oviposition decisions appear to be guided by bacteria-derived semiochemicals as the bacteria	0.07%	8.0
Citrobacter freundii Species-level Match	RISB0517	Leptinotarsa decemlineata Order: Coleoptera	affect the cellular and humoral immunity of the insect, increasing its susceptibility to Bacillus thuringiensis var. tenebrionis (morrisoni) (Bt)	0.12%	8.0
Stenotrophomonas maltophilia Species-level Match	RISB1227	Delia antiqua Order: Diptera	six bacteria protect larvae from infection with the entomopathogen Beauveria bassiana through symbiotic bacterium-derived organic acids	0.28%	8.0
Candidatus Portiera aleyrodidarum Species-level Match	RISB2289	Bemisia tabaci Order: Hemiptera	encoding the capability to synthetize, or participate in the synthesis of, several amino acids and carotenoids,	0.69%	7.9
Morganella morganii Species-level Match	RISB1867	Costelytra zealandica Order: Coleoptera	Female beetles were previously shown to use phenol as their sex pheromone produced by symbiotic bacteria in the accessory or colleterial gland	0.07%	7.9
Spiroplasma poulsonii Species-level Match	RISB1346	Drosophila melanogaster Order: Diptera	S. poulsonii protects its host against parasitoid wasps and nematodes by the action of toxins from the family of Ribosome Inactivating Proteins	0.02%	7.9
Citrobacter freundii Species-level Match	RISB0127	Tribolium castaneum Order: Coleoptera	may produce 4,8-dimethyldecanal (DMD) production that is strongly associated with attraction to females and host pheromone communication	0.12%	7.8
Citrobacter freundii Species-level Match	RISB1221	Delia antiqua Order: Diptera	six bacteria protect larvae from infection with the entomopathogen Beauveria bassiana through symbiotic bacterium-derived organic acids	0.12%	7.8
Klebsiella michiganensis Species-level Match	RISB1131	Bactrocera dorsalis Order: Diptera	promotes host resistance to low-temperature stress by stimulating its arginine and proline metabolism pathway in adult Bactrocera dorsalis	0.02%	7.8
Proteus vulgaris Species-level Match	RISB0001	Leptinotarsa decemlineata Order: Coleoptera	produces toxic hydrogen cyanide (HCN) and a mandelonitrile-producing cyanoglucoside, amygdalin, which protect the insect from predation	0.06%	7.8
Sphingobacterium faecium Species-level Match	RISB1226	Delia antiqua Order: Diptera	six bacteria protect larvae from infection with the entomopathogen Beauveria bassiana through symbiotic bacterium-derived organic acids	0.03%	7.7
Candidatus Portiera aleyrodidarum Species-level Match	RISB1973	Bemisia tabaci Order: Hemiptera	a primary symbiont, which compensates for the deficient nutritional composition of its food sources	0.69%	7.7
Frischella perrara Species-level Match	RISB2028	Diceroprocta semicincta Order: Hemiptera	causes the formation of a scab-like structure on the gut epithelium of its host	1.09%	7.7
Spiroplasma poulsonii Species-level Match	RISB2264	Drosophila melanogaster Order: Diptera	Spiroplasma coopts the yolk transport and uptake machinery to colonize the germ line and ensure efficient vertical transmission	0.02%	7.6
Enterobacter asburiae Species-level Match	RISB1700	Plutella xylostella Order: Lepidoptera	play an important role in the breakdown of plant cell walls, detoxification of plant phenolics, and synthesis of amino acids.	0.03%	7.5
Candidatus Nasuia deltocephalinicola Species-level Match	RISB2282	Nephotettix cincticeps Order: Hemiptera	With the antibiotic, nymphal growth was remarkably retarded, and a number of nymphs either died or failed to attain adulthood	0.02%	7.5
Enterobacter cloacae Species-level Match	RISB1699	Plutella xylostella Order: Lepidoptera	play an important role in the breakdown of plant cell walls, detoxification of plant phenolics, and synthesis of amino acids.	0.02%	7.5
Carnobacterium maltaromaticum Species-level Match	RISB1693	Plutella xylostella Order: Lepidoptera	play an important role in the breakdown of plant cell walls, detoxification of plant phenolics, and synthesis of amino acids.	0.02%	7.5
Psychrobacter sp. 28M-43 Species-level Match	RISB1773	Calliphoridae Order: Diptera	it shows physiological adaptation to survival in warmer temperatures and has been previously associated with food spoilage	0.02%	7.5
Staphylococcus gallinarum Species-level Match	RISB0946	Callosobruchus maculatus Order: Coleoptera	The strain encodes complete biosynthetic pathways for the production of B vitamins and amino acids, including tyrosine	0.02%	7.4
Candidatus Nasuia deltocephalinicola Species-level Match	RISB0262	Maiestas dorsalis Order: Hemiptera	are responsible for synthesizing two essential amino acids (histidine and methionine) and riboflavin (vitamin B2)	0.02%	7.3
Proteus sp. ZN5 Species-level Match	RISB2315	Aedes aegypti Order: Diptera	upregulates AMP gene expression, resulting in suppression of DENV infection in the mosquito gut epithelium	0.02%	7.1
Wigglesworthia glossinidia Species-level Match	RISB1786	Glossina morsitans Order: Diptera	Synthesis of a large number of B vitamins, to supplement the host nutritional deficiencies of the diet	0.05%	7.1
Enterobacter cloacae Species-level Match	RISB2217	Thermobia domestica Order: Zygentoma	Mediated by two microbial symbiont, the firebat saggregates in response to the faeces of conspecifics	0.02%	7.0
Escherichia coli Species-level Match	RISB2120	Galleria mellonella Order: Lepidoptera	mediate trans-generational immune priming	1.11%	6.9
Blattabacterium sp. (Mastotermes darwiniensis) Species-level Match	RISB1534	Periplaneta fuliginosa Order: Blattodea	involved in uric acid degradation, nitrogen assimilation and nutrient provisioning	0.01%	6.7
Carnobacterium maltaromaticum Species-level Match	RISB1692	Plutella xylostella Order: Lepidoptera	participate in the synthesis of host lacking amino acids histidine and threonine	0.02%	6.6
Erwinia sp. QL-Z3 Species-level Match	RISB0808	Hypothenemus hampei Order: Coleoptera	might contribute to caffeine breakdown using the C-12 oxidation pathway	0.07%	6.5
Paenibacillus sp. 481 Species-level Match	RISB0813	Hypothenemus hampei Order: Coleoptera	might contribute to caffeine breakdown using the C-9 oxidation pathway	0.05%	6.5
Wigglesworthia glossinidia Species-level Match	RISB2577	Glossina brevipalpis Order: Diptera	provide its tsetse host with metabolites such as vitamins	0.05%	6.2
Blattabacterium cuenoti Species-level Match	RISB0518	Cryptocercus punctulatus Order: Blattodea	collaborative arginine biosynthesis	0.40%	6.1
Lactiplantibacillus plantarum Species-level Match	RISB0674	Drosophila melanogaster Order: Diptera	could effectively inhibit fungal spore germinations	0.05%	6.1
Proteus vulgaris Species-level Match	RISB2460	Bombyx mori Order: Lepidoptera	degradation of cellulose, xylan, pectin and starch	0.06%	6.1
Providencia rettgeri Species-level Match	RISB1001	Anastrepha obliqua Order: Diptera	improve the sexual competitiveness of males	0.16%	6.0
Lysinibacillus fusiformis Species-level Match	RISB1417	Psammotermes hypostoma Order: Blattodea	isolates showed significant cellulolytic activity	0.02%	6.0
Salmonella enterica Species-level Match	RISB0413	Melanaphis sacchari Order: Hemiptera	None	0.92%	5.9
Carnobacterium maltaromaticum Species-level Match	RISB1691	Plutella xylostella Order: Lepidoptera	activity of cellulose and hemicellulose	0.02%	5.8
Providencia rettgeri Species-level Match	RISB1169	Bactrocera dorsalis Order: Diptera	Promote the growth of larvae	0.16%	5.7
Erwinia sp. QL-Z3 Species-level Match	RISB1986	Bombyx mori Order: Lepidoptera	producing cellulase and amylase	0.07%	5.7
Chryseobacterium sp. T16E-39 Species-level Match	RISB2092	Aedes aegypti Order: Diptera	axenic larvae cannot develop	0.04%	5.6
Chryseobacterium sp. Chry.R1 Species-level Match	RISB2092	Aedes aegypti Order: Diptera	axenic larvae cannot develop	0.03%	5.6
Chryseobacterium sp. IHB B 17019 Species-level Match	RISB2092	Aedes aegypti Order: Diptera	axenic larvae cannot develop	0.02%	5.6
Bombilactobacillus bombi Species-level Match	RISB0617	Spodoptera frugiperda Order: Lepidoptera	degrade amygdalin	0.09%	5.4
Lysinibacillus fusiformis Species-level Match	RISB1066	Oryctes rhinoceros Order: Coleoptera	gut microbe	0.02%	5.2
Candidatus Erwinia haradaeae Species-level Match	RISB1632	Lachninae Order: Hemiptera	None	0.15%	5.2
Flavobacterium johnsoniae Species-level Match	RISB0659	Melanaphis bambusae Order: Hemiptera	None	0.06%	5.1
Lactiplantibacillus plantarum Species-level Match	RISB0608	Drosophila melanogaster Order: Diptera	None	0.05%	5.1
Candidatus Karelsulcia muelleri Species-level Match	RISB1591	Philaenus spumarius Order: Hemiptera	None	0.05%	5.1
Rickettsia prowazekii Species-level Match	RISB1905	Bemisia tabaci Order: Hemiptera	None	0.04%	5.0
Candidatus Annandia pinicola Species-level Match	RISB1661	Adelgidae Order: Hemiptera	None	0.03%	5.0
Candidatus Carsonella ruddii Species-level Match	RISB0748	Diaphorina citri Order: Hemiptera	None	0.02%	5.0
Rickettsia typhi Species-level Match	RISB1906	Bemisia tabaci Order: Hemiptera	None	0.01%	5.0
Candidatus Legionella polyplacis Species-level Match	RISB1687	Polyplax serrata Order: Phthiraptera	None	0.01%	5.0
Candidatus Palibaumannia cicadellinicola Species-level Match	RISB1594	Graphocephala coccinea Order: Hemiptera	None	0.01%	5.0
Candidatus Megaera polyxenophila Species-level Match	RISB0587	Multiple species Order: None	None	0.01%	5.0
Treponema	RISB2377	termite Order: Blattodea	when grown together, two termite-gut Treponema species influence each other's gene expression in a far more comprehensive and nuanced manner than might have been predicted based on the results of previous studies on the respective pure cultures	0.10%	5.0
Photorhabdus	RISB2532	Manduca sexta Order: Lepidoptera	produces a small-molecule antibiotic (E)-1,3-dihydroxy-2-(isopropyl)-5-(2-phenylethenyl)benzene (ST) that also acts as an inhibitor of phenoloxidase (PO) in the insect host Manduca sexta.	0.02%	3.8
Pectobacterium	RISB1889	Pseudococcus longispinus Order: Hemiptera	a nested symbiotic arrangement, where one bacterium lives inside another bacterium,occurred in building the mosaic metabolic pathways seen in mitochondria and plastids	0.02%	3.4
Dickeya	RISB1086	Rhodnius prolixus Order: Hemiptera	supply enzymatic biosynthesis of B-complex vitamins	1.98%	3.0
Photorhabdus	RISB2573	Manduca sexta Order: Lepidoptera	the bacteria are symbiotic with entomopathogenic nematodes but become pathogenic on release from the nematode into the insect blood system	0.02%	2.8
Bacteroides	RISB0090	Hyphantria cunea Order: Lepidoptera	enhance the compatibility of invasive pests to new hosts and enable more rapid adaptation to new habitats.	0.60%	2.7
Vibrio	RISB1810	Monochamus galloprovincialis Order: Coleoptera	Have the ability for degradation of cellulose, proteins and starch	1.36%	2.7
Shewanella	RISB1924	Anopheles gambiae Order: Diptera	may be related with mediating adaptation to different ecological niches or in shaping specific adult behaviors including mating	0.12%	2.7
Yersinia	RISB0492	Cimex hemipterus Order: Hemiptera	the disruption of the abundant Yersinia possibly could be related to the enhanced susceptibility towards the insecticides	0.11%	2.5
Streptococcus	RISB2625	Galleria mellonella Order: Lepidoptera	suppress bacteria ingested with food by producing bacteriocin and by releasing a lysozyme like enzyme	0.37%	2.4
Blautia	RISB0091	Hyphantria cunea Order: Lepidoptera	enhance the compatibility of invasive pests to new hosts and enable more rapid adaptation to new habitats.	0.12%	2.2
Streptococcus	RISB2624	Reticulitermes flavipes Order: Blattodea	can be broken down into substances such as carbon dioxide, ammonia and acetic acid	0.37%	2.0
Agrobacterium	RISB0710	Fragariocoptes setiger Order: Trombidiformes	it appears to form a biologically important association with the mite	0.49%	1.9
Streptococcus	RISB2604	Homona magnanima Order: Lepidoptera	influence the growth of Bacillus thuringiensis in the larvae	0.37%	1.6
Nostoc	RISB0812	Hypothenemus hampei Order: Coleoptera	might contribute to caffeine breakdown using the C-18 oxidation pathway	0.13%	1.6
Leuconostoc	RISB0812	Hypothenemus hampei Order: Coleoptera	might contribute to caffeine breakdown using the C-18 oxidation pathway	0.02%	1.4
Dysgonomonas	RISB1235	Hermetia illucens Order: Diptera	provides the tools for degrading of a broad range of substrates	0.02%	1.3
Paraclostridium	RISB0028	Sesamia inferens Order: Lepidoptera	degrade Chlorpyrifos and Chlorantraniliprole in vitro	0.19%	1.3
Photorhabdus	RISB0532	Drosophila melanogaster Order: Diptera	produces toxin complex (Tc) toxins as major virulence factors	0.02%	1.2
Pectobacterium	RISB0798	Pseudoregma bambucicola Order: Hemiptera	may help P. bambucicola feed on the stalks of bamboo	0.02%	1.1
Aeromonas	RISB2456	Bombyx mori Order: Lepidoptera	able to utilize the CMcellulose and xylan	0.02%	0.8
Cedecea	RISB1570	Bactrocera tau Order: Diptera	could attract male and female B. tau	0.01%	0.7
Mycobacterium	RISB1156	Nicrophorus concolor Order: Coleoptera	produces Antimicrobial compounds	0.02%	0.7
Priestia	RISB0839	Helicoverpa armigera Order: Lepidoptera	producing amylase	0.30%	0.6
Turicibacter	RISB0451	Odontotaenius disjunctus Order: Coleoptera	degrading ellulose and xylan	0.04%	0.6
Aeromonas	RISB2086	Aedes aegypti Order: Diptera	axenic larvae cannot develop	0.02%	0.6
Agrobacterium	RISB0650	Melanaphis bambusae Order: Hemiptera	None	0.49%	0.5
Peribacillus	RISB1877	Aedes aegypti Order: Diptera	gut microbiome	0.14%	0.4
Aeromonas	RISB1145	Tenebrio molitor Order: Coleoptera	degrading plastics	0.02%	0.4
Myroides	RISB0626	Musca altica Order: Diptera	None	0.30%	0.3
Neisseria	RISB0512	Plutella xylostella Order: Lepidoptera	None	0.18%	0.2
Vagococcus	RISB0042	Aldrichina grahami Order: Diptera	None	0.13%	0.1
Treponema	RISB0169	Reticulitermes flaviceps Order: Blattodea	None	0.10%	0.1
Helicobacter	RISB0662	Melanaphis bambusae Order: Hemiptera	None	0.10%	0.1
Metabacillus	RISB0902	Myzus persicae Order: Hemiptera	None	0.08%	0.1
Candidatus Phytoplasma	RISB1620	Cacopsylla pyricola Order: Hemiptera	None	0.06%	0.1
Apibacter	RISB1138	Musca domestica Order: Diptera	None	0.05%	0.1
Candidatus Profftia	RISB1664	Adelgidae Order: Hemiptera	None	0.05%	0.1
Cupriavidus	RISB0694	Alydus tomentosus Order: Hemiptera	None	0.03%	0.0
Candidatus Arthromitus	RISB2613	Multiple species Order: None	None	0.03%	0.0
Pectobacterium	RISB1772	Muscidae Order: Diptera	None	0.02%	0.0
Dysgonomonas	RISB1481	Brachinus elongatulus Order: Coleoptera	None	0.02%	0.0
Paraburkholderia	RISB0125	Physopelta gutta Order: Hemiptera	None	0.02%	0.0
Cedecea	RISB0504	Plutella xylostella Order: Lepidoptera	None	0.01%	0.0